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Dr Rajkumar Banerjee, Faculty Scientist, Applied Biology Division, CSIR-IICT, Hyderabad, delivered a lecture on the topic “Reactive oxygen species- From Concepts to Therapeutics for Cancer” at PGR Conference Hall, MCOPS, 亚洲通_亚洲通官网 on 16 October 2023. Dr Banerjee elucidated the dual functionality of specific chemotherapeutic agents, including quinones, nitrogen mustards, nitrosoureas, and nucleosides, which act as a two-edged sword in cancer therapy. These compounds serve both as cytotoxic agents and as inducers of ROS.

Dr Banerjee emphasized on the substantial modifications in glycolysis, a fundamental metabolic pathway, leading to a phenomenon known as “Warburg effect” in cancer. He also highlighted that elevating the pH of the tumour microenvironment and reducing the build-up of acidic compounds may hold promise for mitigating tumour aggressiveness. This lecture was a preamble to the next session scheduled on 17 October 2023.